However, the UKB GWAS shows significant association of sleep medication purchase for SNPs at alpha level 0.05 for a quarter of the loci (8 from 27 loci) including signal the canonical sleep genes MEIS1 (rs11693221, β = 0.006, p = 0.01) and PAX8 (rs62158170, β = −0.003, p = 0.02) and with the schizophrenia associated TSNARE1 (rs13262595, β = −0.002, p = 0.03) and CACNA1C (rs2370413, β = 0.001, p = 0.04) signals but for example not with the GABRA locus. This evidence concerns the gene PAX8 and schizophrenia.