Ying et al. [52] showed that exosomal miR-222-3p derived from epithelial ovarian cancer (EOC) cells polarizes TAMs-like macrophages into the M2 phenotype through suppression of the cytokine signaling 3 (SOCS3)/signal transducer and activator of transcription 3 (STAT3) signaling axis, accelerating the progression of EOC. This evidence concerns the gene STAT3 and ovarian carcinoma.