TP53 and non-Hodgkin lymphoma: Focusing on the mutation patterns of TP53 and ARID1A, point mutations in the DNA-binding domain (DBD) were the main type for TP53. The TP53 R248 W/V/Q (4 vs. 2) mutation was more common in IR MB-NHL, but the TP53 R273H/C (8 vs. 3) mutation was more common in r/r MB-NHL patients.