Other significant risk factors for HCC recurrence were age (HR 0.95, P = 0.004), BMI (HR 0.92, P = 0.033), pre-transplant MELD scores (HR 0.94, P = 0.017), log AFP (HR 1.18, P = 0.018), bridging treatment (HR 0.21, P = 0.001 for none; HR 2.38, P = 0.003 for systemic or radiotherapy versus locoregional treatment), viable tumor number (HR 1.07, P = 0.006), maximum tumor size (HR 1.13, P = 0.044), microvascular invasion (HR 2.14, P = 0.005), and acute rejection within 3 months (HR 2.10, P = 0.006). The gene discussed is AFP; the disease is hepatocellular carcinoma.