Among them, SLC25A1 expression showed positive relevance with CD8 + T cells (R = 0.128, P = 8.89e-03), macrophage (R = 0.268, P = 2.69e-08)and B cells (R = 0.186, P = 1.34e-04) but negative correlation with CD4 + T cells (R = − 0.217, P = 7.83e-06), neutrophils (R = − 0.213, P = 1.23e-05) and myeloid dendritic cells (R = − 0.192, P = 8.20e-05) in PRAD. This evidence concerns the gene CD4 and prostate adenocarcinoma.