Using the gene chip data in Kaplan–Meier Plotter, we found that SLC25A1 was a high-risk gene in lung cancer (OS: HR = 1.6, log-rank P = 1.2e-08; FP: HR = 1.9, log-rank P = 2.3e-07), gastric cancer (OS: HR = 1.81, log-rank P = 7.2e-11; FP: HR = 1.75, log-rank P = 6.1e-08; PPS: HR = 2.42, log-rank P = 1.31e-15) and breast cancer (OS: HR = 1.4, log-rank P = 0.00043; PPS: HR = 1.34, log-rank P = 0.013) (Fig. 5A–G), but a gene of low risk in ovarian cancer (OS: HR = 0.8, log-rank P = 0.00083; PPS: HR = 0.76, log-rank P = 0.0016) (Fig. 5H, I). This evidence concerns the gene SLC25A1 and lung cancer.