Thus, we aimed to understand the molecular profile of aAA patients, by studying the mRNA expression of NOTCH-1, its ligands (DLL-1 and JAG-1), and T helper cell transcription factors (namely T-BET, GATA-3, and ROR-γT) in both PB and BM of aAA patients and healthy controls. Here, GATA3 is linked to triple-A syndrome.