CD4 and bladder transitional cell carcinoma: We next estimated immune cell composition by using CIBERSORTx, a digital cytometry from bulk tissues [15] (Supplementary Table 5), and revealed distinct infiltration patterns of various immune cell types in BLCA according to FGFR3 status, including B naïve cells, B memory cells, T-CD4 + memory resting cells, T-follicular helper cells, M0 macrophages, dendritic cell proportions (Fig. 4C-D).