Notably, we further explored whether RPLP2 upregulation was linked to ferroptosis in seven other cancers where RPLP2 was most significantly upregulated, and the results indicated that RPLP2 also showed significant correlation with GPX4 in five cancer types including GBM, LGG, PAAD, TGCT and THYM (Additional file 1: Fig. S7A). Here, GPX4 is linked to glioblastoma.