ROC curve analysis revealed that with an increase in time, the predictive efficiency of MET, CLDN9, MIOX, and CHST4 for the prognosis of GC patients improved, while TKTL1 was not suitable for predicting the survival time of GC patients (Additional file 2: Figure S2-Additional file 6: S6C). Here, TKTL1 is linked to gastric cancer.