Interestingly, we found elevated levels of ARG1-positive myeloid cells predominantly inside the metastatic tumour, consistent with previous reports showing similar results in 4T1 [36] and PyMT-BO1 [40] metastatic breast tumours as well as colon carcinoma, lymphoma and melanoma [37] and glioma [41] mouse models. Here, ARG1 is linked to colon carcinoma.