IL1A and cancer: The clinical database of Gene Expression Profiling of Interactive Analysis (GEPIA) also revealed that, in the case of colon adenocarcinoma (COAD), the cancers (Fig. 5g, red lines) highly expressing the inflammatory-related genes, IL1A, IL1B, and CXCL8, significantly exhibited better overall survival ratios compared to that of cancers of low expression of these genes (Fig. 5g, blue lines and Table S1).