To confirm the effects of TAK-931 on tumor infiltration of immune cells in more detail, the dissociated allografts were also subjected to FCM-based immune profiling panel studies, which classified various immune cell types based on extracellular or intracellular immune markers (Fig. S12c): CD45+ for hematopoietic cells (except for mature erythrocytes and platelets), CD45+CD3+ for T cells, CD45+CD3+CD8+ for cytotoxic T cells, and CD45+CD3+CD4+ for helper T cells. Here, CD8A is linked to neoplasm.