Several studies have shown that the main pathways of β-elemene anti-NSCLC include the AMP-activated protein kinase/mitogen-activated protein kinases (AMPK/MAPK), phosphoinositide 3-kinase (PI3K)/AKT/mechanistic target of rapamycin (mTOR) and FAK-Src pathways6,8,14. Here, MTOR is linked to non-small cell lung carcinoma.