Anti-hypertensive agents in 15% (18/132), lipid lowering agent in 10% (12/132), Levothyroxine in 8% (9/132), Allopurinol in 2% (3/132), NSAIDS in 2% (2/132), oral anti-diabetic/insulin in 12% (14/132), anticoagulant in 2% (2/132), antidepressant in 2% (3/132) and other medications (anti-hyperuricemic, urine alkalinizer, anti-migraine agent, corticosteroids, benzodiazepine) in 12% (14/132) were reported. This evidence concerns the gene INS and migraine disorder.