Among PD-resistant DaNs, the most resilient subtype SOX6−_SORCS3 was characterized by expression of both FOXP2 and SORCS3, with its PD-induced genes involved in exocytosis microtubule-related terms such as “regulation of exocytosis”, “microtubule-based movement” and “microtubule-based transport”. The gene discussed is SORCS3; the disease is Parkinson disease.