Furthermore, by comparing the mRNA levels of SOAT1 in glioma tissues and corresponding normal tissues in a comprehensive dataset (TCGA-GBM plus TCGA-LGG), the mRNA level of SOAT1 in glioma was significantly upregulated, and the expression of SOAT1 increased with an increase in tumor grade (Fig. 1E). This evidence concerns the gene SOAT1 and glioma.