ADAMTSL4 and spontaneous coronary artery dissection: A separate GWAS study of SCAD (analyzed in an initial discovery study with 270 cases and 5263 controls and replication study with 263 cases and 3207 controls) based upon a prospective, multi-center SCAD registry, found an association at chromosome 1q21.2 with rs12740679 influencing ADAMTSL4 gene expression, and this gene was strongly prioritized through colocalization analysis (combining the GWAS result and an eQTL analysis of arterial tissue mRNA expression in GTEx).