To further characterize the biological effects of Cd, the two different Luminal A cell lines were exposed to 0.5 and 1 μM Cd for 6 h and the effect of this exposure on the phosphoinositide 3-kinase (PI3K)/AKT and MAPK pathways were evaluated, since alteration of these pathways is often present in this type of tumor. The gene discussed is AKT1; the disease is neoplasm.