Besides, it may reduce systolic and diastolic blood pressure [56], be associated with a reduced risk of type 2 diabetes mellitus by increasing insulin sensitivity [57] and is shown to be inversely associated with inflammatory marcers [58] including C-reactive protein, interleukin-6, and tumor necrosis factor-α [58–60] which all are health-affecting factors. This evidence concerns the gene INS and type 2 diabetes mellitus.