Gene expression pattern analysis of CDK6, TNRC6B, and AGO1 was significantly decreased in high-risk PCa patients’ samples compared to their lower-risk counterparts (Fig. 5a), whereas the expression of AGO3 and TNRC6A genes showed no significant differences between low and high-risk groups (Fig. 5a). Here, TNRC6B is linked to posterior cortical atrophy.