In addition, ECIG alters immune response against influenza infection and reduces survival from infection [7], furthermore, the role of lipid receptor in viral entry and replication has been implicated [42]. Our correlation analysis revealed that lipid accumulation was positively associated with lipid peroxidation, CD36 expression and M1 MQ polarization, on the other hand lipid accumulation was negatively correlated with the rate of phagocytosis and expression of the phagocytic receptors CD35 and CD64. This evidence concerns the gene CD36 and influenza.