Based on the method of network pharmacology, we found that there were 15 common genes in atherosclerosis and NSCLC, including CD163, MMP9, ACP5, FABP4, EMCN, CD52, NPR1, MMP12, C2, ITLN1, FHL5, CD36, FIBIN, C7, and NPNT. Here, FHL5 is linked to non-small cell lung carcinoma.