Therefore, after adjusting for the tumor stage in the multivariate Cox model survival analysis, the survival time of GC patients with high CST4 immunohistochemical expression was significantly different from that of GC patients with low CST4 immunohistochemical expression (P = 0.015, HR = 1.76, 95% CI = 1.76–2.78) (Table 7). This evidence concerns the gene CST4 and neoplasm.