To explore the hub m6A regulators in pulpitis, we further constructed the molecular interaction network of m6A-related genes, and Cytoscape was used to extract the interaction network of core genes (Fig. 3), which further suggested that these genes RBM15B, METTL16, METTL14, YTHDF3 and ALKBH5 may be the main regulators in pulpitis m6A-modified genes. This evidence concerns the gene METTL16 and pulpitis.