In addition, the gene expression levels of ALKBH5, METTL3, METTL14, METTL16, RBM15B, YTHDF1, YTHDF3 and ZCCHC4 were detected in the collected human dental pulp tissue samples, and it was found that the expression of METTL14 in pulpitis was lower than that in the control group. The gene discussed is ZCCHC4; the disease is pulpitis.