From previous study of docking results shows that N4 (inhibitor) which are STAT3 inhibitor interacted with STAT3-SH2 at multiple amino acid residues some are following LYS591, SER636, VAL637, AND GLU63831 STAT3 inhibitor i-e S31-201with compounds which improved bioavailability and anti-cancer properties. The gene discussed is STAT3; the disease is cancer.