The objective of the present study has been refined as follows: This research endeavored to assiduously explore the consequences of engaging in walking exercise of moderate intensity quantitatively defined as a regimen involving 7000–9999 steps per day at a pace of 100 steps per minute22 on several health parameters, including body mass index, hs-CRP, IL-6, TNF-α, and VEGF levels, among postmenopausal women navigating through obesity. This evidence concerns the gene IL6 and Obesity.