HLA-C and B-cell chronic lymphocytic leukemia: Allotype specific peptide alignment of the most abundant HLA allotypes within the cohort (HLA-A*02, HLA-B*35 and HLA-C*07, Supplemtary Fig. 4g–i) even revealed CLL-exclusive peptides with presentation in up to 100% of HLA-matching samples (HLA-A*02 up to 100%, HLA-B*35 up to 100% and HLA-C*07 up to 50%) representing highly promising, broadly applicable antigen targets for immunotherapeutic approaches.