To confirm whether TNRC6A was a direct target of miR-652-3p in HCC, next the mutant of TNRC6A was constructed (Figure 4C)and perform dual luciferase assays, Our data present that the luciferase activities were notably deceased after co-transfection of wild type TNRC6A 3’ UTR and miR-652-3p mimics. The gene discussed is TNRC6A; the disease is hepatocellular carcinoma.