RAD21 and atrial fibrillation: Remarkably, the mutations led to AF predicting with high confidence and in five out five models the unpacking of Scc1N’s first two helices and their docking with Wapl’s CTD (Figure 28, f52A) in a manner very similar, if not identical, to that observed when the first two or three helices are run alone with Wapl’s CTD (Figure 26A) or in AF predictions for Wapl’s association with isolated Scc1 NTDs (Figure 25, f34).