SOAT1 and Alzheimer disease: This study was the first to explore the feasibility of Bi2-xMnxO3 nanospheres (BM) in agar gel as STAT phosphorylation regulators to improve the clinical manifestations in MC903-induced atopic dermatitis (AD)—like C57BL/6 mice, and to evaluate their immunomodulatory effects in vitro and in vivo.