CRPPA and neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan: (d) Several subtypes of LGMDs are dystroglycanopathies, primarily caused by mutations in eight genes, including FKRP (R9), POMT1 (R11), FKTN (R13), POMT2 (R14), POMGnT1 (R15), GMPPB (R19), ISPD (R20), and POMGNT2 (R24), involved in the glycosylation of the alpha-dystroglycan pathway [15].