In the multivariate regression analysis, higher ESR (≥ 20 mm/h, OR, 3.58; 95% CI 1.21 to 11.19, P = 0.023), higher IL-10 levels (OR, 1.19; 95% CI, 1.02–1.41, p = 0.038), positivity for MDA-5 antibodies (OR, 5.47; 95% CI, 1.11–33.43, P = 0.045) were found to be significantly associated with JDM-ILD (Fig. 2C). The gene discussed is IL10; the disease is interstitial lung disease.