Overall, mean IL-1β detected in the saliva of participants with CHD (AS-P, 194.15 pg/mL; AS-C, 123.29 pg/mL) and periodontitis alone (P, 78.43 pg/mL), were significantly higher than the control group (C, 5.94 pg/mL) (F value = 17.97, p < 0.001). Here, IL1B is linked to coronary artery disorder.