IL1B and periodontitis: Therefore, as miR-155 has been proposed as a potentially viable biomarker of inflammation and disease activity, the primary objective of this study was to accurately quantify whole blood miR-155 expression and salivary pro-inflammatory cytokine, interleukin-1β (IL-1β), protein levels in generalized periodontitis patients, with or without additionally diagnosed CHD, versus periodontal healthy patient control groups, with or without diagnosed CHD.