In this study, a miRNA-mRNA network was constructed which contains miR-206-3p, miR-493-5p, miR-493-3p, miR-193b-3p, miR-200a-3p, miR-29a-3p, miR-29b-3p, miR-29c-3p, Bfsp1, Plp1, Cnp, Nfasc, Mbp, Pygm, Bfsp2 and Fn1, whose dysregulation may be associated with the cataract pathogenesis. The gene discussed is MBP; the disease is cataract.