At 10 months post-infection, there was a significant decrease of both S-specific CD4 + and CD8 + T cells (Median: S-small pool: 0.11% and 0.05% for CD4 + and CD8 + T cells, respectively; S-large pool: 0.69% and 0.42% for CD4 + and CD8 + T cells, respectively). The gene discussed is CD4; the disease is infection.