Since \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$${\rm{TNF}}{\rm{\alpha }}$$\end{document}TNFα cytokine is secreted in large quantities by immune cells in a tumor microenvironment74, varying extent of dynamic TNFR1 signaling is continuously occurring in a population of cancer cells. The gene discussed is TNFRSF1A; the disease is cancer.