BRAF and colorectal carcinoma: Recent studies indicate that aberrant activation of Wnt/β‐catenin signaling, one of the essential features in the development and occurrence of CRC,[10] is closely related to the refractoriness of BRAF V600E CRC.[11] However, the underlying molecular basis linking Wnt/β‐catenin signaling and BRAF V600E‐mediated chemoresistance warrant further investigation.