The presence of alpha‐synuclein‐immunoreactive glial cytoplasmic inclusions (GCIs), associated with prominent neuronal loss and astrogliosis in the striatonigral (SN) or olivopontocerebellar (OPC) systems, constitutes the neuropathological hallmark of MSA [3, 4]. The gene discussed is SNCA; the disease is multiple system atrophy.