In that study, the association between serum APOC3 and CVD risk remained significant when adjusted for age, sex, blood pressure, BMI, HbA1c, diabetes duration, smoking status, kidney function measured as estimated glomerular filtration rate (eGFR), insulin use, LDL-cholesterol, HDL-cholesterol, and triglycerides. This evidence concerns the gene APOC3 and diabetes mellitus.