Indeed, we additionally evaluated some cases of Pick’s disease (3R-tauopathy) and one further case with the 4-repeat tauopathy, LNT.14 Interestingly, we found no PNS-tau lesions in the Pick’s disease cases (Supplementary Table 2), while p-tau-positive deposits were present in the PNS in LNT (Supplementary Fig. 1). This evidence concerns the gene MAPT and Pick disease.