WMS can result from variants in FBN1 (WMS2) or other genes including ADAMTS10 (WMS1), LTBP2 (WMS3), and ADAMTS17 (WMS4) (Faivre et al. 2003b; Hubmacher and Apte 2011). The gene discussed is ADAMTS10; the disease is Weill-Marchesani syndrome.