VEGF-C156S posttreatment also increased the percentage area and the relative fluorescence intensities of lymphatics in the pLNs in LPS/CLP-induced sepsis (Figure 4, B and D, and Supplemental Figure 8, B and D) and reduced the accumulation of macrophages (F4/80+CD45.2+ cells or CD68+ cells) and neutrophils (LY6G+ cells) in the lung, while increasing these cells in pLNs (Figure 5, Supplemental Figure 11, and Supplemental Figure 12, A–C). The gene discussed is VEGFA; the disease is Sepsis.