We examined pulmonary lymphatic vessels marked with Prox1-tdTomato (red) and VEGFR-3 immunofluorescence (green) at 6 hours, 12 hours, 24 hours, and 48 hours in LPS-induced sepsis mice and found that the diameter of pulmonary lymphatic vessels was increased at 6 hours and decreased subsequently (Figure 3, B and C). Here, FLT4 is linked to Sepsis.