To analyze if the beneficial effects of FGD and DMF were related to a decrease in the presence of mediators related to these pathways, we analyzed by western blot the presence of some representative components of these pathways, such as gasdermin-D (GSDM-D), P65/NFkB, and SOCS3. This evidence concerns the gene NFKB1 and Aarskog-Scott syndrome, X-linked.