S100B and breast cancer: Indeed, human leukocyte antigen (HLA) class I-restricted escape mutations were apparent in the five participants who initiated ART in advanced chronic infection; these included the C*06:02-restricted Nef-125H adaptation (77) at position 6 of the C*06-restricted-YT9 epitope (Nef 120–128) (78, 79) in BC-001, the C*07:01-restricted Nef-105Q adaptation (77) at position 1 of the C*07-restricted KY11 epitope (Nef 120–128) (77) in BC-003, the B*35:01-restricted Nef-81F adaptation (77) at the C-terminus of the B*35:01-restricted VY8 epitope (Nef 74–81) (80) in BC-027, and others.