Overall, our findings are in line with previous studies carried out in yeast (Kruzel-Davila et al., 2017), cultured human podocytes, APOL1 transgenic mice (Beckerman et al., 2017; McCarthy et al., 2021) and the age-related changes observed in patients with APOL1-associated kidney diseases (Abid et al., 2020; Hoy et al., 2015). Here, APOL1 is linked to kidney disorder.