The ratio of SOD1/GPx3 significantly decreased along with the growing prevalence of the endometriosis (P = 0.0048; 0.324 ± 0.110) and endometrial cancer (P = 0.0003; 0.123 ± 0.027) compared with the healthy controls (1.154 ± 0.336). Here, GPX3 is linked to endometriosis.