Among the 412 bladder cancer samples, 42 (10.19%) experienced mutation in the 8 SiaTs which were ST6GALNAC1, ST3GAL6, ST8SIA2, ST6GAL2, ST6GAL1, ST6GALNAC5, ST6GALNAC3, and ST3GAL5 (Fig. 1C). The gene discussed is ST8SIA2; the disease is urinary bladder cancer.