SiaTs_Cluster A exhibited a greater enrichment of activated B cells (Fig. 3E), activated CD4 T cells (Fig. 3F), activated CD8 T cells (Fig. 3G), natural killer T cells (Fig. 3H), macrophages (Fig. 3I), and neutrophils (Fig. 3J), etc.; while CD56dim natural killer cells (Fig. 3B), monocytes (Fig. 3C) and type 17 T helper cells (Fig. 3D) were enriched in SiaTs_Cluster B. According to these findings, the SiaTs represented crucial relationship with immune infiltration, which might serve as a potential contributor to bladder cancer. This evidence concerns the gene CD8A and urinary bladder cancer.