Double Mvp+/−;Mapk3+/− male mice showed normal body weight (Additional file 1: Fig. S12A) as well as normal motricity, coordination, reward-seeking behaviors, working and short-term memory, associative learning, circadian activity, and no signs of autism and schizophrenic-like behaviors (Additional file 1: Fig. S12B-K). The gene discussed is MAPK3; the disease is autism.