In a 12-week double-blind intervention consisting of 5 g/day of the thylakoid membranes from spinach powder with low-calorie diet, Tabrizi FP et al. documented significant decreases in weight, waist circumference, fat mass, and insulin levels in PCOS individuals from the spinach-derived thylakoid group compared to the placebo group [28]. This evidence concerns the gene INS and polycystic ovary syndrome.