We also found that these genes (prognostic genes) are involved in biological processes and pathways that are linked to cancer (Fig. 1E and F), such as signaling by ALK in cancer [19], cell-cell adhesion [20], signaling by receptor tyrosine kinase [21], PID INTEGRIN A4B1 pathway [22], gliogenesis [23], positive regulation of cell adhesion [24] and VEGFA-VEGFR2 signaling pathways [25, 26]. The gene discussed is KDR; the disease is cancer.