NPPB and hydrops fetalis: The beneficial effects of CRT in responders include reverse cardiac remodelling (reduced left ventricular volumes and increased LVEF), improvement of New York Heart Association (NYHA)-based functional status, symptoms and quality of life, reduction of brain natriuretic peptide (BNP), improvement in the six-minute walk test (6MWT), and reduction of mortality and HF hospitalization [11, 12].